TREND Reporting Guidelines for Nonrandomized/Quasi-Experimental Study Designs (2024)

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    Guide to Statistics and Methods

    Reporting Guidelines

    April 7, 2021

    Alex B.Haynes,MD, MPH1; Jason S.Haukoos,MD, MSc2,3,4; Justin B.Dimick,MD, MPH5,6

    Author Affiliations Article Information

    • 1Department of Surgery and Perioperative Care, Dell Medical School, University of Texas, Austin

    • 2Department of Emergency Medicine, Denver Health Medical Center, University of Colorado School of Medicine, Denver

    • 3Department of Epidemiology, Colorado School of Public Health, Aurora

    • 4Statistical Editor, JAMA Surgery

    • 5Department of Surgery, University of Michigan Health System, Ann Arbor

    • 6Section Editor, JAMA Surgery

    JAMA Surg. 2021;156(9):879-880. doi:10.1001/jamasurg.2021.0552

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    Full Text

    The Transparent Reporting of Evaluations with Nonrandomized Designs (TREND) guidelines were first published in 2004, in response to the perceived value and effect of the Consolidated Standards of Reporting Trials (CONSORT) guidelines that had been introduced a decade earlier.1 The initial development of these guidelines was spearheaded by the US Centers for Disease Control and Prevention HIV/AIDS Prevention Research Synthesis team. The initial interest was specifically in standardization of the reporting of behavioral interventions in HIV/AIDS (eg, interventions to improve adherence to antiretroviral therapy or to increase frequency of partner testing), but the group broadened its interest to include all evaluations of interventions using nonrandomized designs. The guideline authors, comprising researchers, policy makers, and journal editors, developed a reporting framework that was based on the CONSORT guidelines but adapted for evaluation of interventions other than randomized trials.

    • Editorial Effective Use of Reporting Guidelines to Improve the Quality of Surgical Research

      JAMA Surgery

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    Haynes AB, Haukoos JS, Dimick JB. TREND Reporting Guidelines for Nonrandomized/Quasi-Experimental Study Designs. JAMA Surg. 2021;156(9):879–880. doi:10.1001/jamasurg.2021.0552

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